Serial ports disappear after years of working reliably

I have several projects that have been using the Serial library reliably for years. Recently, on all of my computers (using Macintoshes) the /dev/cu.usbserial-XXXX port has disappeared. The Bluetooth ports are still there when listed. This puts me dead in the water. They also are not listed in Terminal. Help would be appreciated, because I’m in a pickle.

Do you have some device plugged into your usb port(s)? They only show up in Terminal output when you are using them on my MacOS system (M4 Tahoe 26.5).

You should see all of them listed when you type this into Terminal:

ls /dev/{tty,cu}.*